Relationships Among Serum Pepsinogen I, Serum Pepsinogen II, and Gastric Mucosal Histology

Estimation of serum pepsinogen.

Tissue and serum pepsinogen I and II in gastric cancer identified using immunohistochemistry and rapid ELISA.

AIMS To investigate the immunohistochemical expression and the serum concentrations of pepsinogen I and II in different histological types of gastric cancer as compared with other gastric disorders. METHODS Formalin fixed, paraffin wax embedded tissue specimens of 38 gastric cancers obtained from surgical cases were used for the immunohistochemical studies performed with the avidin-biotin com...

Serum Gastrin and the Pepsinogen I/II Ratio for Diagnosis of Gastric Lesions

Gastric cancer (GC), despite a recent gradual decline in incidence, is still one of the most common malignancies worldwide and remains the second most common leading cause of cancer death causing more than 700,000 deaths annually worldwide (Parkin et al., 2000; Axon, 2002; Parkin, 2004; Yanaoka et al., 2008). In 2002, an estimated one million new cases of gastric cancer were diagnosed, with alm...

serum gastrin 17, pepsinogen i and pepsinogen ii in atrophic gastritis patients living in north-east of iran

normal 0 false false false en-us x-none ar-sa background: gastric carcinoma is the second most common cause of cancer-related death in iran. it is well-known that atrophic gastritis is a major risk factor for gastric cancer, which leads to variations in the serum levels of gastrin 17 (g-17), pepsinogen i (p-i), and pepsinogen ii (p-ii). the aim of this study was to investigate the diagnostic ac...

Serum gastrin 17, pepsinogen I and pepsinogen II in atrophic gastritis patients living in North-East of Iran

BACKGROUND Gastric carcinoma is the second most common cause of cancer-related death in Iran. It is well-known that atrophic gastritis is a major risk factor for gastric cancer, which leads to variations in the serum levels of gastrin 17 (G-17), pepsinogen I (P-I), and pepsinogen II (P-II). The aim of this study was to investigate the diagnostic accuracy of these serum biomarkers in the early d...